Математическое моделирование лазер-индуцированного тромбоза в кровеносных сосудах

Abstract

The hierarchical chain of mathematical models of laser – induced thrombosis in microvessels is developed. Richardson’s phenomenological model is extended to describe the realistic feature of phenomenon. The main directions of the generalization are the dependence of platelet activation time on the distance from the injured vessel wall and the non-homogeneity of the platelet distribution in blood flow in the vicinity of the vessel wall. The generalization of the model corresponds to the main experimental results and theoretical considerations concerning thrombus formation obtained in recent years.